Figure 5

Divergence of stage-specific gene co-expression among bovine, human and mouse oocytes and embryos. (A). Heatmap of gene overlap between independently constructed bovine and human modules. The X- and Y-axes show human (n = 9) and bovine stage-specific modules (n = 12), respectively. Each cell contains the number of intersecting genes and the corresponding P-value (-log10) of the intersection. Significant gene overlaps were found in nearly all stages of development between the human and bovine. (B). Heatmap of gene overlap between independently constructed bovine and mouse modules. The X- and Y-axes show mouse (n = 9) and bovine stage-specific modules (n = 12), respectively. Each cell contains the number of intersecting genes and the corresponding P-value (-log10) of the intersection. Significant gene overlaps were only observed in oocytes and morula/blastocysts between the bovine and mouse.