Figure 6

Code-based classification of Pol2-bound promoters and enhancers in ES cells. Parameters of a multivariate penalized logistic regression model using code variables. Codes and their weights were obtained by the "discriminatory" algorithm. (A) Basis patterns associated with the six coefficients with the largest magnitude (B) Coefficients of all basis patterns, where positive and negative values indicate propensity towards TSS-proximal and TSS-distal regions, respectively. In total 12 codes were trained: 6 on TSS-proximal and 6 on TSS-distal regions. The weights in W were reconstructed using all 12 basis patterns (Figure1C).