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Figure 7 | BMC Genomics

Figure 7

From: Combinatorial epigenetic patterns as quantitative predictors of chromatin biology

Figure 7

"gain-loss" codes of epigenetic reprogramming during differentiation. Graphical representation of the H factor matrix of the "differential" algorithm. Rows correspond to "gain-loss" basis patterns, columns to both gains and losses of epigenetic marks. The height of each bar is equal to the loading of a mark gain or loss on a code. Columns are grouped based on the direction of epigenetic change ("gain" or "loss"). Within a single code it is rare to observe both a significant "gain" and "loss" of the same mark. Most mark changes have significant loading in two codes with the exception of H3K9me3 gain and H3K27me3 loss. The majority of patterns combines "gains" and "losses"of multiple marks.

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