Table 1 Transcription factors (TFs) with the highest number of binding sites on the promoter regions of up-regulated genes during pneumococcal pathogenesis
TF | Lungs vs nasopharynx | Blood vs lungs | Brain vs blood | |||||
|---|---|---|---|---|---|---|---|---|
WCH16 | WCH43 | D39 | WCH16 | WCH43 | D39 | WCH16 | WCH43 | |
SP_0927 (smrC) | 13 | 4 | Â | Â | 3 | 115 | 18 | 18 |
SP_1073 (rpoD) | 74 | 23 | 17 | 3 | 26 | 767 | 94 | 113 |
SP_1113 (hup) | 26 | 10 | 4 | 2 | 4 | 249 | 36 | 39 |
SP_1227 (rr02) | 20 | 4 | 6 | 1 | 6 | 137 | 31 | 31 |
SP_1584 (codY) | 19 | 3 | Â | Â | 8 | 175 | 28 | 25 |
SP_1725 (scrR) | 16 | 4 | 1 | Â | 1 | 72 | 15 | 17 |
SP_2077 (argR) | 14 | 7 | 1 | 4 | 7 | 201 | 17 | 23 |