Figure 4From: Different nucleosomal architectures at early and late replicating origins in Saccharomyces cerevisiaeOrigin accessibility is increased in the absence of Rpd3. Aggregated nucleosomal profiles of 318 NDR associated with replication origins (A) or 320 NDR non-associated with origins (B) from G1-arrested WT (blue) and rpd3Δ (red) cells were aligned relative to the ACS or to the NDR center, respectively. (C), Average NDR width of replication origins (left graph) or non-origin regions (right graph) from WT (blue) and rpd3Δ mutants (red). (D), As in A but for early origins. (E), As in A but for late origins. (F), As in C but for early (left graph) and late origins (right graph). (G), Nucleosome patterns around the late origins ARS 603 and ARS 423 from WT (blue) and rpd3Δ samples (red). Hyper-acetylated regions in the rpd3 mutant (Robyr et al., [31]; Vogelauer et al. [9]) are represented in green. Black arrows point to nucleosomes affected in the absence of Rpd3.Back to article page