Figure 1

L1 length distributions of missed events. A and B show the length distributions of L1 events that are not detected by Tangram and RetroSeq, respectively. The red line is the L1 length distribution of the 1,000 L1 elements introduced in the simulated data. The blue line represents the missed events in 10X data and the green line represents the missed events in 20X data. Tangram (A) detected almost all the severely truncated events whereas RetroSeq (B) is not sensitive enough to those short L1 elements.