Figure 2

Breakpoint resolution for A (AluY) and B (L1). The difference between reported and true breakpoint position in simulated data is shown for the Tangram and the RetroSeq MEI detection algorithms (homozygous events in 106 bp paired-end reads, 20X sequence coverage for AluY simulation and heterozygous events in 106 bp paired end reads, 20X sequence coverage for L1 simulation). The majority of breakpoints reported by Tangram exactly match the true breakpoint.