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Table 9 Comparison of PCR validation results across three MEI detection algorithms

From: Tangram: a comprehensive toolbox for mobile element insertion detection

 

Tangram

RetroSeq

VariationHunter

 

Random

Novel

Combined

Random

Novel

Combined

Random

Novel

Combined

Analyzed by PCR

80

78

158

80

80

159

83

51

134

Validated Loci

77

69

142

73

58

131

69

29

98

Invalidated Loci

2

7

9

7

21

28

14

22

36

FDR

2.53%

9.21%

5.96%

8.75%

26.58%

17.61%

16.87%

43.14%

26.86%

  1. Calls were made in 23 1000 Genomes Project Phase 1 samples by Tangram, RetroSeq and VariationHunter.