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Figure 2 | BMC Genomics

Figure 2

From: Next-generation sequencing identifies equine cartilage and subchondral bone miRNAs and suggests their involvement in osteochondrosis physiopathology

Figure 2

Between Class Analysis (BCA) based on A- cartilage and B- bone miRnomes. BCA succeed in discriminating between healthy samples (H) and predisposed samples of OC-affected foals (OC), as well as healthy samples loaded (H_L) and unloaded (H_UL) in both cartilage and bone. This suggests that miRNA may be involved in OC physiopathology and biological response to mechanical loading. In contrast, BCA does not well discriminate between healthy samples loaded (H_L) and OC predisposed samples loaded (OC_L) in cartilage and bone. This may prove that biomechanical response is not disrupted in cartilage and bone predisposed samples of OC-affected foals.

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BMC Genomics

ISSN: 1471-2164

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