Table 1 Differentially expressed neuroendocrine genes in the brains of sexually mature and immature male eels

+

1.99

Calcium/calmodulin-dependent protein kinase kinase 2-like isoform X1

Calcium signaling

498924960

+

1.52

Calcium-binding protein 4

Calcium signaling

62901497

+

1.79

Calmodulin-like

Calcium signaling

499017111

+

2.25

Cocaine- and amphetamine-regulated transcript ch22 precursor

Feeding, neuroendocrine signaling, neuronal development

325652192

+

2.73

Cocaine- and amphetamine-regulated transcript protein

Feeding, neuroendocrine signaling, neuronal development

301610675

+

3.85

Cocaine- and amphetamine-regulated transcript protein-like

Feeding, neuroendocrine signaling, neuronal development

410898200

+

2.12

Collagen alpha-2(V) chain

Calcium, collagen

143811378

+

1.67

Corticotropin-releasing factor-binding protein precursor

Neuroendocrine signaling

51010999

+

4.4

C-type natriuretic peptide 1 precursor

Neuropeptide signaling, energy metabolism

317575753

+

4.35

C-type natriuretic peptide 1-like

Neuropeptide signaling, energy metabolism

348526229

+

2.51

C-type natriuretic peptide 3-like precursor

Neuropeptide signaling, energy metabolism

192455608

+

1.56

Developmentally-regulated GTP-binding protein 2-like isoform X1

Development

1706518

+

1.67

Fibroblast growth factor receptor 1

Regulation of development, differentiation and migration

120047

+

9.78

Galanin peptides-like isoform 1

Neuroendocrine signaling

348532269

+

3.75

Glutamate decarboxylase 1-like

Neurotransmitter biosynthesis (GABA synthesis)

348538615

+

2.03

Growth arrest-specific protein 1

Developmental protein

30923264

+

2.02

Heat shock 70 kDa protein-like

Chaperone

326665952

+

2.02

heat shock 70 kDa protein-like

Chaperone

2495346

+

1.9

High affinity cGMP-specific 3'',5''-cyclic phosphodiesterase 9A

GPCR signaling, neuronal processes

326670632

+

4.02

Homeobox protein HMX2

Neurogenesis and differentiation

27735196

+

2

Homeobox protein HMX2

Neurogenesis and differentiation

152032526

+

2.48

Homeobox protein SIX1

Developmental protein, transcription regulation

2495290

+

1.97

Immunoglobulin superfamily containing leucine-rich repeat protein 2 precursor

Neurogenesis and differentiation

61806620

+

5.28

Insulin gene enhancer protein ISL-3-like

Neuroendocrine signaling

348500124

+

4.62

Iroquois-class homeodomain protein irx-2

Neurogenesis and differentiation

82181198

+

2.11

Iroquois-class homeodomain protein IRX-3

Developmental protein, transcription regulation

47117874

+

4.89

Iroquois-class homeodomain protein irx-3

Neurogenesis and differentiation

82185674

+

5.5

Iroquois-class homeodomain protein IRX-3

Developmental protein, transcription regulation

262527548

+

1.54

Iroquois-class homeodomain protein IRX-5

Neurogenesis and differentiation

143811406

+

1.63

Mammalian ependymin-related protein 1 precursor

Cell matrix adhesion

50539892

+

1.63

Mammalian ependymin-related protein 1-like

Cell matrix adhesion

499037681

+

2.46

Membrane-associated progesterone receptor component 1

Neuroendocrine signaling

318102138

+

1.78

Metalloproteinase inhibitor 2

Protease inhibitor

267133

+

2.47

Natriuretic peptide precursor C-like protein precursor

Neuropeptide signaling

238624212

+

1.83

Neuroendocrine protein 7B2-like isoform 2

Neuropeptide signaling

292624780

+

2.14

Neurogenic differentiation factor 1

Neurogenesis and differentiation

82227588

+

6.39

Neuropeptide B-like

Feeding, neuroendocrine signaling, neuronal development

348536652

+

2.22

Neuropeptide Y-like

Feeding, Neuroendocrine signaling

327274623

+

1.68

Neuropeptide-like protein C4orf48 homolog precursor

Developmental protein

213510972

+

2.53

Prodynorphin precursor

Neuropeptide signaling

317574783

+

2.4

Protachykinin-1 precursor

Neuropeptide signaling

317575728

+

2.57

Stanniocalcin-1

Calcium signaling

505851525

+

2.67

Tachykinin 3a precursor

Neuropeptide signaling

373838776

+

1.64

Transcription factor HES-4

Retinogenesis, neurogenesis and differentiation

82202542

+

2.53

Transcription factor HES-5

Developmental protein, transcription regulation

3913838

+

2.29

Type I iodothyronine deiodinase

Thyroid hormone biosynthesis

348504600

+

5.03

Type III iodothyronine deiodinase a

Thyroid hormone biosynthesis

209954616

+

9.85

Type III iodothyronine deiodinase b

Thyroid hormone biosynthesis

209954618

+

1.51

Zinc finger protein ZIC 1

Neurogenesis and differentiation

82243612

+

1.9

Zinc finger protein ZIC 2-A

Neurogenesis and differentiation

223634664

-

0.59

Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha

Calcium signaling

154147642

-

0.62

Calcium/calmodulin-dependent protein kinase II inhibitor 2

Calcium signaling

223029393

-

0.65

Calmodulin

Calcium signaling

224004208

-

0.48

Cyclic AMP-dependent transcription factor ATF-3

Transcription regulation

41055726

-

0.42

Cytochrome P450 3A18

Hydroxylation of testosterone

21955148

-

0.66

G protein-coupled receptor kinase 4-like

GPCR signaling

292609536

-

0.58

Glutamate receptor subunit epsilon-2

Ion transport

190358411

-

0.51

Heat shock 90 kDa protein 1 beta isoform b

Chaperone

185136252

-

0.6

Heat shock protein HSP 90-beta-like

Chaperone

392356281

-

0.63

Insulin receptor substrate 2-B-like

Insulin signaling

348540607

-

0.27

Insulin receptor substrate 2-B-like

Insulin signaling

504156832

-

0.41

Interferon-induced transmembrane protein 5-like

Bone mineralization

432860359

-

0.61

Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog

Transcription regulation

348534997

-

0.64

Prodynorphin precursor

Neuropeptide signaling

213514964