Skip to main content
Figure 5 | BMC Genomics

Figure 5

From: Application of experimentally verified transcription factor binding sites models for computational analysis of ChIP-Seq data

Figure 5

ROC (Receiver operating characteristic) of TFBS models (A) and CC (correlation coefficient) (B). A – ROC curves for 8 recognition models applied to ChIP-Seq data [25]. ‘J’ - JASPAR PWM, ‘Tr’ - TRANSFAC PWM. The fraction of recognized peaks (X axis) shows the true positive (TP) rate. The fraction of recognized shuffled peaks (Y axis) shows the false positive (FP) rate. Markers for each model show the point corresponding to the EMSA-derived threshold. B – the correlation coefficients reflect balance between TP and FP rates computed for thresholds derived from EMSA verification. The values of TP and TP rates are shown in ROC curves (A) by markers.

Back to article page