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Table 3 T. gondii DEGs that were more abundant >5-fold in acute vs chronic infection

From: Dual transcriptional profiling of mice and Toxoplasma gondii during acute and chronic infection

Gene ID

Description

Fold change: acute/chronic

TGME49_233480

SAG-related sequence SRS29C (SRS29C)

305

TGME49_233460

SAG-related sequence SRS29B (SAG1)

181

TGME49_291890

microneme protein MIC1 (MIC1)

41

TGME49_241240

hypothetical protein

40

TGME49_224460

aminopeptidase

26

TGME49_262050

rhoptry kinase family protein ROP39

23

TGME49_297880

dense granule protein DG32

19

TGME49_271050

SAG 34A/SAG/2

18

TGME49_294200

glucose-6-phosphate 1-dehydrogenase

13

TGME49_230160

hypothetical protein

12

TGME49_261740

hypothetical protein

12

TGME49_291960

rhoptry kinase family protein ROP40

10

TGME49_268850

enolase 2

9

TGME49_277490

hypothetical protein

9

TGME49_215960

hypothetical protein

9

TGME49_222170

dense-granule antigen DG32

8

TGME49_293430

hypothetical protein

8

TGME49_262730

rhoptry protein ROP16 (ROP16)

8

TGME49_314400

pyruvate dehydrogenase E1 component

8

TGME49_315320

SAG-related sequence SRS52A (SRS52A)

7

TGME49_200360

hypothetical protein

7

TGME49_285870

SAG-related sequence SRS20A (SRS20A)

7

TGME49_269950

hypothetical protein

7

TGME49_247280

hypothetical protein

7

TGME49_294800

elongation factor 1-alpha (EF-1-ALPHA)

7

TGME49_213050

hypothetical protein

6

TGME49_249180

bifunctional dihydrofolate reductase-thymidylate synthase

6

TGME49_226710

hypothetical protein

6

TGME49_237880

hypothetical protein

6

TGME49_250115

hypothetical protein

6

TGME49_254720

dense granule protein GRA8 (GRA8)

6

TGME49_253930

GCC2 and GCC3 domain-containing protein

6

TGME49_299780

hypothetical protein

6

TGME49_275860

hypothetical protein

6

TGME49_310780

dense granule protein GRA4 (GRA4)

6

TGME49_277080

microneme protein MIC5 (MIC5)

6

TGME49_226960

phosphofructokinase PFKII (PFKII)

6

TGME49_243730

rhoptry protein ROP9 (ROP9)

6

TGME49_207400

hypothetical protein

6

TGME49_259240

ribosomal protein RPS21 (RPS21)

6

TGME49_205340

ribosomal protein RPS12 (RPS12)

6

TGME49_209150

non-proton pumping type-II NADH dehydrogenase I (NDH2-I)

6

TGME49_253690

hypothetical protein

5

TGME49_229670

ribosomal protein RPS23 (RPS23)

5

TGME49_244690

hypothetical protein

5

TGME49_212290

ribosomal protein RPS19 (RPS19)

5

TGME49_288360

tryptophanyl-tRNA synthetase (TrpRS2)

5

TGME49_251810

translation initiation factor eIF-5A

5

TGME49_200350

subtilisin SUB3 (SUB3)

18*

TGME49_250955

KRUF family protein

21*

TGME49_279350

hypothetical protein

23*

TGME49_313250

hypothetical protein

26*

TGME49_307760

Tubulin-tyrosine ligase family protein

27*

TGME49_315740

SAG-related sequence SRS54

27*

TGME49_243700

hypothetical protein

29*

TGME49_293210

hypothetical protein

30*

TGME49_276110

cytochrome b5 family heme/steroid binding

34*

TGME49_218740

membrane protein

65*

TGME49_294805

hypothetical protein

77*

TGME49_294990

hypothetical protein

106*

TGME49_216770

hypothetical protein

125*

TGME49_230180

hypothetical protein

129*

TGME49_305050

calmodulin

295*

  1. First column is the gene number from ToxoDB.org. The second column is the gene description. The far right column is the average FPKM value from acute infection divided by the average FPKM value from chronic infection, called the fold change. * in the fold change column indicates the average FPKM value during chronic infection was 0, and could not be divided by the average FPKM value in acute samples. A p-value and q-value of <0.05 was considered to be statistically significant and only genes that met these standards were included on this table.