Figure 6

Ionizing radiation induces alterations in microRNA expression levels. Differentially expressed miRNAs in irradiated versus non-irradiated PBMCs are shown. The heat map shows 177 miRNAs that were differentially expressed 20 hours after irradiation. Samples obtained 20 hours after irradiation formed a cluster visible on the right side of the figure, whereas prior time points did not cluster according to treatment or time. The range of expression was from −5 (green, down-regulation) to 5 (red, up-regulation). The names of the genes are given on the right border of the heat map. Sample labeling: “2” = 2 hours, “4” = 4 hours, “20” = 20 hours, “▬” = 0 h sample; “□” = non-irradiated sample; “■” = irradiated sample.