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Figure 1 | BMC Genomics

Figure 1

From: Genome-wide Twist1 occupancy in endocardial cushion cells, embryonic limb buds, and peripheral nerve sheath tumor cells

Figure 1

Twist1 genomic occupancy in endocardial cushions, limb buds, and peripheral nerve sheath tumor cells. A. Twist1 binding regions were identified by ChIP-seq followed by MACS analysis in E12.5 ECCs, E10.5 limb buds, and PNST cells compared to a control strain matched whole genome dataset. The total number of peaks, the number of peaks within 50 kilobases (Kb) of a transcriptional start site (TSS), and the number of peaks associated with expressed genes, as determined by microarray gene expression analysis of the tissue of interest, are shown. B. The total number of shared peaks detected by Twist1 ChIP-seq of ECC-Limb, Limb-PNST, ECC-PNST and ECC-Limb-PNST groups is shown. The number of overlapping peaks within 50 kb of a TSS for expressed genes also was determined.

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