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Table 3 Networks ranking with relative molecules symbols list, score value, number of molecules belonging to the dataset (Focus molecules) and top function for each network

From: iTRAQ-proteomics and bioinformatics analyses of mammary tissue from cows with clinical mastitis due to natural infection with Staphylococci aureus

ID

Molecules in network

Score

Focus molecules

Top functions

1

A2M, ALB, ALDH2, ALDH1A1, Alp, Alpha catenin, ANXA6, Ap1, APOA4, calpain, chymotrypsin, COL1A1, COL1A2, COL6A1, COL6A2, COL6A3, collagen, Collagen Alpha1, Collagen type I, Collagen type III, Collagen type IV, Collagen type VI, Collagen(s), CP, DCN, DES, elastase, ERK1/2, FBN1, FGA, FGB, FGG, Fibrin, Fibrinogen, FLNA, FN1, Focal adhesion kinase, GPIIB-IIIA, Growth hormone, HBA1/HBA2, HDL, HP, HSPG2, IL1, Immunoglobulin, Integrin, ITIH4, KRT8, Laminin, Ldh, LDL, Mmp, P38 MAPK, Pak, Pdgf (complex),PDGF BB, Pka, Rock, S100A9, S100A12, SERPINA3, SERPINH1, Smad, Stat3-Stat3, T3-TR-RXR, Tgf beta, TGM2, THBS1, trypsin, Vegf

68

31

Organismal Injury and Abnormalities, Dermatological Diseases and Conditions, Hereditary Disorder

2

Actin, ADCY, ADM, Akt, Alpha Actinin, ANGPTL1, caspase, CD3, CD27, CD226, CSK, Cytokeratin, D-mannose, ERK, F Actin, Fascin, FKBP1A, GCNT1, GRB7, HBB, hemoglobin, HIST1H1C, Histone h3, Ige, Igf, IgG, IL12 (complex), IL17R, Il3r, Insulin, ITGB8, Jnk, KRT19, L-isoleucine, LCN2, LCP1, LYPLA1, MAPK13, Mapk, MAZ, MB, MYBPH, MYH9, MYH10, MYL1, MYL4, MYL6, MYO15A, Myosin, NEB, NFkB (complex), PER1, PI3, PI3K (complex), PIGR, Pkc(s), PLA2R1, PTPRCAP, PVRL2, Rac, Ras, S100, S100A8, S100A12, SLC5A3, SORBS1, Sos, TCR, TLR2/TLR4, TMPRSS6

25

14

Lymphoid Tissue Structure and Development, Organ Morphology, Cancer

3

AKT1, ALDH1B1, ATP5J2, Casein, COPS8, CORO1B, CPB2, Csn1s1, DAZAP1, DDX18, DIMT1, Fascin, FGA, GAR1, GLUD1, GPI, HNRNPA1L2, Igf, Il3r, IPO4, ITGAX, ITGB8, KIAA1524, KIDINS220, LAP3, LCP1, MDN1, MMP16, MRPS34, MT-CYB, MTHFR, MTM1, MYBPH, MYC, MYL1, NDUFA5, NDUFS2, NOP58, NUAK1, NUP205, PDCD11, PELI2, PGS1, PI4KA, PPA1, PVRL2, SAP130, SEC22B, SLC1A4, SLC20A1, SLC25A1, SLC40A1, SORBS1, SRM, ST6GAL1, Thbs1, THBS2, TIA1, TIAL1, TNF, Top2, TRAP1, UBC, UNC5B, UQCR10, UQCR11, UQCRB, UQCRFS1, Wap, YARS

12

8

Cell Cycle, Cardiovascular Disease, Cell Morphology

4

CLDN24,cldn

2

1

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