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Figure 3 | BMC Genomics

Figure 3

From: A systematic analysis of protein palmitoylation in Caenorhabditis elegans

Figure 3

Locomotive behaviour in solution is mostly unaffected by disruption of palmitoylation enzymes. Thrashing assays were performed on animals deficient for DHHC enzymes, either mutant strains (A) or feeding RNAi-treated hypersensitive rrf-3 mutants (C) and compared with wild-type Bristol N2 or empty L4440 vector control respectively. Similarly, thrashing assays were performed on mutant strains (B) and feeding RNAi-treated rrf-3 mutants (D) for the PPT enzymes. (E) Closely related pairs of enzymes were knocked down by feeding RNAi and subjected to thrashing assays. n = 30–288 animals, from 3–14 independent experiments for mutants; and 10–49 animals, from 1–5 independent experiments for RNAi. *p < 0.05 by one-way ANOVA.

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