Figure 5

Comparison of the whole genome gene expression profile of amastigotes using Pro-Pper or cultured promastigotes as reference. The profiles of cultured logarithmic and stationary phase promastigotes compared with amastigotes have been published [23]. (A) Venn diagrams contrasting differential gene expression in L. infantum amastigotes depending on the origin of promastigotes. (B) Relative expression and classification (MEV analysis) in clusters of genes showing similar patterns or opposite expression profiles in amastigotes depending on the source of promastigotes (see a complete overview of the clustering analysis in Additional file 5).