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Figure 1 | BMC Genomics

Figure 1

From: Genetic and epigenetic regulation of gene expression in fetal and adult human livers

Figure 1

Study design and distribution of CpG sites. (A) Study design describing the investigated biomaterials and analyses performed. *) conservation compared across tissues; #) compared in fetal vs adult livers. (B) Distribution of the location of differentially methylated CpG sites between fetal and adult livers. The bar plot shows the percentage of differentially methylated CpG sites (y-axis) that are hypermethylated (black bars) or hypomethylated (grey bars) in fetal livers compared to adult livers in CpG islands, shores, shelves and other regions of the genome. (C) Distribution of differentially expressed and methylated genes depending on the relation to CpG islands. Pie charts illustrating the distribution of CpG island regions in case of significant increased or decreased gene expression and significant hyper- or hypomethylation.

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