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Table 2 Gene Ontology analysis of differentially expressed genes in fetal versus adult liver

From: Genetic and epigenetic regulation of gene expression in fetal and adult human livers

A. Top 10 biological processes associated with hyperexpressed genes in adult livers
Term P-value Nr of genes
Monocarboxylic acid metabolic process 2.80E-205 347
Lipid localization 8.26E-202 201
Lipid transport 1.99E-197 180
Steroid metabolic process 2.91E-196 257
Bile acid metabolic process 1.13E-192 40
Response to xenobiotic stimulus 9.88E-184 114
Cellular response to xenobiotic stimulus 9.88E-184 114
Xenobiotic metabolic process 6.72E-183 113
Bile acid biosynthetic process 6.23E-178 23
Response to glucocorticoid stimulus 2.61E-173 131
B. Top 10 biological processes associated with hyperexpressed genes in fetal livers
Term P-value Nr of genes
Negative regulation of organelle organization 3.93E-162 138
Regulation of organelle organization 1.73E-132 370
Negative regulation of cellular component organization 3.40E-127 265
Regulation of chromosome organization 1.61E-114 72
Porphyrin-containing compound biosynthetic process 1.84E-112 34
Tetrapyrrole biosynthetic process 1.84E-112 34
Negative regulation of chromosome organization 6.05E-108 29
Chromatin assembly or disassembly 8.76E-106 128
Pigment biosynthetic process 1.73E-103 53
G1 phase 6.25E-102 36