Figure 6

Merge analysis of sequence variants. The x-axis is genome location, y-axis is the logP of the test of association between locus and survival. The continuous black lines are sections of the genome scans in Figure 4. The blue dots are the results of merge analysis tests of sequence variants segregating in the 8 founders of the CC. For clarity, the great majority of variants with merge logP < 1 are not shown. Biallelic SNPs are in red circles, SNPs with more than two alleles (caused when alleles are unknown in one or more founders, which are then treated as unknown private alleles) are dark blue triangles. Image taken from the genome scan viewer http://mus.well.ox.ac.uk/gscandb. A. Kprl1 on chromosome 4; B. Kprl2 on chromosome 8 and C. Kprl3 on chromosome 18.