Skip to main content

Table 5 Example of genes differentially expressed by morphine in our study and identified in other species

From: Whole-genome expression profile in zebrafish embryos after chronic exposure to morphine: identification of new genes associated with neuronal function and mu opioid receptor expression

Probeset ID Genename Description/validation in silico R.fold Species Reference
Up‐regulation
Dr.9852.1.A1_at camk1γb Calcium/calmodulin‐dependent protein kinase Igb 2,16 Mouse [12]
Dr.23925.1.A1_at soat1 Sterol O‐acyltransferase (acyl‐Coenzyme A: cholesterol acyltransferase) 1 1,69 Rat [16]
Dr.19223.1.S2_at aldocb Aldolase C, fructose‐bisphosphate, b 1,49 Rat [105]
Dr.11457.1.S1_at zbtb16 Zinc finger and BTB domain containing 16 1,44 Mouse [12, 65]
Dr.12489.1.S1_at mlf1 Myeloid leukemia factor 1 1,44 Mouse [8]
Dr.18505.1.S1_at ccnt1 Cyclin‐T1 1,44 Mouse [6]
Dr.822.1.S3_at cxcl12a Chemokine (C‐X‐C motif) ligand 12a (stromal cell‐derived factor 1) 1,38 Mouse [8]
Dr.23722.1.S1_at cyp27a1.4 Cytochrome P450, family 27, subfamily A, polypeptide 1, gene 4 1,35 Mouse [8]
Dr.9423.1.S1_at ndufb2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8 kDa 1,31 Mouse [6]
Dr.867.1.S1_at wdr1 WD repeat domain 1 1,28 Rat [105]
Dr.12378.1.S1_at hspb1 Heat shock protein, alpha‐crystallin‐related, 1 1,27 Rat & mouse [16, 55]
Dr.3645.1.S1_at plg Plasminogen 1,26 Rat & mouse [12, 15]
Down‐regulation
Dr.3663.1.A1_at dao.1 D‐amino‐acid oxidase 1 −1,94 Rat [51, 52]
Dr.9860.1.S1_at mdh1b Malate dehydrogenase 1b, NAD (soluble) −1,79 Rat [105]
Dr.19735.1.S1_at phyhd1 Phytanoyl‐CoA dioxygenase domain containing 1 −1,56 Mouse [55]
Dr.5687.1.A1_at hspb8 Heat shock protein, alpha‐crystallin‐related, b8 −1,45 Mouse [8, 55]
Dr.737.1.A1_at junbb Jun B proto‐oncogene b −1,36 Rat & mouse [7]
Dr.3546.1.S1_at wls wntless homolog (Drosophila) −1,25 Mouse [10]