Skip to main content

Table 5 Example of genes differentially expressed by morphine in our study and identified in other species

From: Whole-genome expression profile in zebrafish embryos after chronic exposure to morphine: identification of new genes associated with neuronal function and mu opioid receptor expression

Probeset ID

Genename

Description/validation in silico

R.fold

Species

Reference

Up‐regulation

Dr.9852.1.A1_at

camk1γb

Calcium/calmodulin‐dependent protein kinase Igb

2,16

Mouse

[12]

Dr.23925.1.A1_at

soat1

Sterol O‐acyltransferase (acyl‐Coenzyme A: cholesterol acyltransferase) 1

1,69

Rat

[16]

Dr.19223.1.S2_at

aldocb

Aldolase C, fructose‐bisphosphate, b

1,49

Rat

[105]

Dr.11457.1.S1_at

zbtb16

Zinc finger and BTB domain containing 16

1,44

Mouse

[12, 65]

Dr.12489.1.S1_at

mlf1

Myeloid leukemia factor 1

1,44

Mouse

[8]

Dr.18505.1.S1_at

ccnt1

Cyclin‐T1

1,44

Mouse

[6]

Dr.822.1.S3_at

cxcl12a

Chemokine (C‐X‐C motif) ligand 12a (stromal cell‐derived factor 1)

1,38

Mouse

[8]

Dr.23722.1.S1_at

cyp27a1.4

Cytochrome P450, family 27, subfamily A, polypeptide 1, gene 4

1,35

Mouse

[8]

Dr.9423.1.S1_at

ndufb2

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8 kDa

1,31

Mouse

[6]

Dr.867.1.S1_at

wdr1

WD repeat domain 1

1,28

Rat

[105]

Dr.12378.1.S1_at

hspb1

Heat shock protein, alpha‐crystallin‐related, 1

1,27

Rat & mouse

[16, 55]

Dr.3645.1.S1_at

plg

Plasminogen

1,26

Rat & mouse

[12, 15]

Down‐regulation

Dr.3663.1.A1_at

dao.1

D‐amino‐acid oxidase 1

−1,94

Rat

[51, 52]

Dr.9860.1.S1_at

mdh1b

Malate dehydrogenase 1b, NAD (soluble)

−1,79

Rat

[105]

Dr.19735.1.S1_at

phyhd1

Phytanoyl‐CoA dioxygenase domain containing 1

−1,56

Mouse

[55]

Dr.5687.1.A1_at

hspb8

Heat shock protein, alpha‐crystallin‐related, b8

−1,45

Mouse

[8, 55]

Dr.737.1.A1_at

junbb

Jun B proto‐oncogene b

−1,36

Rat & mouse

[7]

Dr.3546.1.S1_at

wls

wntless homolog (Drosophila)

−1,25

Mouse

[10]