Table 1 Demographics of the TPCH-KCO set (n = 29 patients) used in microRNA microarrays
From: MicroRNA-34c is associated with emphysema severity and modulates SERPINE1 expression
| Â | TPCH-KCO set | |
|---|---|---|
Mild emphysema | Moderate emphysema | |
n | 9 | 20 |
Age (Mean ± SD yrs) | 70 ± 4 | 67 ± 7 |
Range | 63-74 | 53-78 |
Male/Female | 7/2 | 14/6 |
FEV1 % predicted (Mean ± SD) | 80 ± 17 | 68 ± 15 |
Range | 52-107 | 50-97 |
FEV1/VC (Mean ± SD) % | 59 ± 5 | 54 ± 14 |
Range | 50-70 | 40-70 |
KCO % predicted (Mean ± SD) | 79 ± 3 | 66 ± 9 |
Range | 75-85 | 38-74 |
Pack years (Mean ± SD) | 62 ± 34 | 75 ± 49 |
Range | 28-135 | 24-240 |
Site of tissue collection | 1-LLL | 1-LL |
1-RLL | 5-LUL | |
1-LL | 7-RLL | |
1-RL | 5-RUL | |
5-RUL | 2-RML | |
GOLD Stage I Mild (FEV1 ≥80% predicted) | 4 | 3 |
GOLD Stage II Moderate (50 < FEV1 < 80% predicted) | 5 | 17 |