Table 3 Top Ten under-expressed and over-expressed genes in MDS vs control muscle
Gene name | Description | FC | FDR |
|---|---|---|---|
Under-expressed | Â | Â | Â |
ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | -9.1 | 0 |
FBP2 | Fructose-1,6-bisphosphatase 2 | -9.1 | 0 |
MYLK2 | Myosin light chain kinase 2 | -7.1 | 0 |
ANKRD23 | Ankyrin- repeat domain containing protein 23 | -7.1 | 0 |
ACTN3 | Actinin, alpha 3 | -6.9 | 0 |
AQP4 | Aquaporin 4 | -6.2 | 5.88E-04 |
GLUL | Glutamine synthase | -5.9 | 0.002 |
SMTNL2 | Smoothelin-like 2 | -6.2 | 2.86E-04 |
ARRDC2 | Arrestin domain containing 2 | -5.8 | 2.86E-04 |
TRIM63 | Tripartite motif containing 63, E3 ubiquitin protein ligase | -5.5 | 0.002 |
PYGM | Glycogen phosphorylase | -4.8 | 0.001 |
Over-expressed | Â | Â | Â |
GDF15 | Growth Differentiation Factor 15 | 188 | 0 |
MYH8 | Myosin Heavy Chain Embryonic | 119 | 0 |
TRIB3 | Tribbles homolog 3 | 47 | 0 |
MYH3 | Myosin Heavy Chain Neonatal | 24 | 0 |
SNAR-A3 | Small nuclear ILF3/NF90-associated RNA A3 | 23 | 0 |
TNNT2 | Troponin T2, cardiac | 21 | 0 |
DEFB1 | Defensin beta-1 malignant brain tumours 1 | 16 | 0 |
TMEM63C | Transmembrane protein 63C | 16 | 0 |
DMBT1 | Deleted in malignant brain tumors 1 | 11.3 | 0 |
COL19A1 | Collagen type XIX | 11 | 0 |