Table 5 Biological functions associated with TK2 deficiency according to Ingenuity Pathway Analysis
Category | Function | P-value | molecules |
|---|---|---|---|
Diseases and disorders | Â | Â | Â |
| Â | Cancer | 1.88E-14 - 1.18E-02 | 253 |
| Â | Neurological Disease | 1.81E-11 - 8.60E-03 | 160 |
| Â | Skeletal and muscular disorders | 1.81E-11 - 8.38E-03 | 166 |
| Â | Cardiovascular disease | 3.52E-09 - 1.14E-02 | 102 |
| Â | Hereditary disorder | 6.31E-08 - 1.18E-02 | 98 |
Molecular and cellular functions | Â | Â | Â |
| Â | Cell death and survival | 2.63E-08 - 1.11E-02 | 165 |
| Â | Cellular function and maintenance | 1.02E-05 - 1.06E-02 | 135 |
| Â | Small molecule biochemistry | 1.02E-05 - 1.18E-02 | 105 |
| Â | Cell signaling | 1.17E-05 - 1.18E-02 | 38 |
| Â | Vitamin and mineral metabolism | 1.17E-05 - 1.18E-02 | 31 |
Physiological system development and function | Â | Â | Â |
| Â | Skeletal and muscular system development and function | 1.22E-20 - 1.18E-02 | 99 |
| Â | Embryonic development | 1.89E-05 - 1.18E-02 | 82 |
| Â | Organ morphology | 1.22E-20 - 1.18E-02 | 80 |
| Â | Organ development | 1.89E-05 - 1.18E-02 | 63 |
| Â | Cardiovascular system Development and function | 1.66E-07 - 8.20E-03 | 57 |