Figure 4From: The chromatin architectural proteins HMGD1 and H1 bind reciprocally and have opposite effects on chromatin structure and gene regulationHMGD1 and H1 are correlated with gene expression. (A) Scatter plots of normalized HMGD1 and (B) H1 versus RNA-seq gene expression. Each data point represents a single gene. The HMGD1 rate is the log2 ratio of HMGD1 midpoints to total nucleosome midpoints from the promoter region -100 to +500Â bp. The H1 rate is calculated similarly but for the region -550 to +50Â bp. (C) Pearson correlations of RNA-seq gene expression with HMGD1 (red), H1 (blue), total nucleosome (black) or the HMGD1/H1 ratio (green). The correlations are computed for non-overlapping genomic regions corresponding roughly to the locations of well-positioned nucleosomes and the nucleosome depleted region (NDR). Vertical line segments represent 95% confidence intervals for the correlations.Back to article page