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Figure 4 | BMC Genomics

Figure 4

From: The chromatin architectural proteins HMGD1 and H1 bind reciprocally and have opposite effects on chromatin structure and gene regulation

Figure 4

HMGD1 and H1 are correlated with gene expression. (A) Scatter plots of normalized HMGD1 and (B) H1 versus RNA-seq gene expression. Each data point represents a single gene. The HMGD1 rate is the log2 ratio of HMGD1 midpoints to total nucleosome midpoints from the promoter region -100 to +500 bp. The H1 rate is calculated similarly but for the region -550 to +50 bp. (C) Pearson correlations of RNA-seq gene expression with HMGD1 (red), H1 (blue), total nucleosome (black) or the HMGD1/H1 ratio (green). The correlations are computed for non-overlapping genomic regions corresponding roughly to the locations of well-positioned nucleosomes and the nucleosome depleted region (NDR). Vertical line segments represent 95% confidence intervals for the correlations.

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