Transcriptional and epigenetic responses to mating and aging in Drosophila melanogaster

BMC Genomics

Table 2 Numbers of candidate histone regulated genes with altered expression after mating or upon aging*

Comparison	H3K4me1		H3K4me3		H3K9ac
	Up-regulated	Down-regulated	Up-regulated	Down-regulated	Up-regulated	Down-regulated
Young flies
Virgin vs. Mated	13	13	12	15	19	20
Virgin flies
Young vs. Aged	4	3	4	5	2	4
Mated flies
Young vs. Aged	5	6	24	18	16	11
Aged flies
Virgin vs. Mated	1	0	0	0	0	0

*Numbers in the table represent genes associated with histone marks. Up-regulated and Down-regulated refer to the histone marks detected by immuno co-precipitation. Differences between conditions were estimated by subtracting histone peak amplitudes in virgin flies from those in mated flies and in young flies from those in aged flies.

ISSN: 1471-2164