Table 3 The list of 34 genes that showed decreased expression level after globin reduction

ENSSSCG00000028278

POLR2A

polymerase (RNA) II (DNA directed) polypeptide A, 220 kDa

ENSSSCG00000022476

–

–

ENSSSCG00000012570

–

–

ENSSSCG00000024020

RERE

arginine-glutamic acid dipeptide (RE) repeats

ENSSSCG00000028814

SOD3

superoxide dismutase 3, extracellular

ENSSSCG00000031032

SLA-DRB3 ^b

MHC class II, DR beta-like 3 pseudogene

ENSSSCG00000006328

RXRG

Retinoic acid receptor RXR-gamma

ENSSSCG00000003562

SFN

stratifin

ENSSSCG00000004389

–

–

ENSSSCG00000000386

ANKRD52

ankyrin repeat domain 52

ENSSSCG00000011331

–

–

ENSSSCG00000010913

–

–

ENSSSCG00000022894

GZMH

granzyme H

ENSSSCG00000027961

–

–

ENSSSCG00000011258

EXOG

endo/exonuclease (5′-3′), endonuclease G-like

ENSSSCG00000022933

EFR3B

EFR3 homolog B (S. cerevisiae) [Source: HGNC Symbol; Acc:29155]

ENSSSCG00000029574

–

–

ENSSSCG00000010915

–

–

ENSSSCG00000022681

–

–

ENSSSCG00000000253

KRT18

keratin 18

ENSSSCG00000029399

–

–

ENSSSCG00000013264

PHF21A

PHD finger protein 21A

ENSSSCG00000009603

–

–

ENSSSCG00000009444

OLFM4

olfactomedin 4

ENSSSCG00000030191

–

–

ENSSSCG00000029430

–

–

ENSSSCG00000023324

KMT2A

lysine (K)-specific methyltransferase 2A

ENSSSCG00000015124

PVRL1

poliovirus receptor-related 1 (herpesvirus entry mediator C)

ENSSSCG00000025712

–

–

ENSSSCG00000013547

CRB3

crumbs homolog 3 (Drosophila)

ENSSSCG00000026303

PROSER1

proline and serine rich 1

ENSSSCG00000003942

–

–

ENSSSCG00000013545

TUBB4A

tubulin, beta 4A class IVa

ENSSSCG00000001513

SYNGAP1

synaptic Ras GTPase activating protein 1