Figure 3

The proportion of synonymous and non-synonymous SNPs. SNPs that are found in a single chromosome among the 16 Turkish genomes (Rare) show a significant increase in the proportion of non-synonymous SNPs (NonSyn) to synonymous SNPs (Syn), as compared to all SNPs observed in the same population (p < 0.01, Chi-square with Yates’ correction). This increase is even more visible among SNPs that are seen in a single chromosome and are novel (i.e., not found in other databases) (NovelRare).