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Figure 4 | BMC Genomics

Figure 4

From: Calcifying vascular smooth muscle cells and osteoblasts: independent cell types exhibiting extracellular matrix and biomineralization-related mimicries

Figure 4

Clustering of genes with similar expression patterns in C-VSMCs and osteoblasts and respective functional annotation of the clusters. (A) Clusters of genes with similar expression pattern for C-VSMCs and osteoblasts were obtained using k-means clustering (k = 6). For these analysis only differentially expressed genes were used. Average relative gene expression level (log2 fold-change relative to day 0) for all probes within each cluster at the different time points analyzed is shown. (B) Functional annotation for each of the 6 clusters in C-VSMCs and osteoblasts. Only significant (Bonferroni p-value < 0.05) biological process, cellular compartment and molecular function annotations were considered for analysis. Numbers within grid represent fold-enrichment levels of GO-terms in the distinct clusters. The number of probes/genes comprised in each cluster is also indicated.

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