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Table 2 GO term enrichment in genes unique to IAF-45-CD

From: Intraspecies comparison of Streptomyces pratensis genomes reveals high levels of recombination and gene conservation between strains of disparate geographic origin

GO ID

Term

All

Unique

Expected

p-value

GO:0006259

DNA metabolic process

92

22

2.39

8.12E-14

GO:0015074

DNA integration

11

10

0.29

7.02E-13

GO:0003676

nucleic acid binding

439

34

11.29

3.40E-07

GO:0044260

cellular macromolecule metabolic process

700

42

18.2

8.12E-07

GO:0090304

nucleic acid metabolic process

555

37

14.43

1.09E-06

GO:0003677

DNA binding

356

29

9.16

3.47E-06

GO:0034641

cellular nitrogen compound metabolic pro…

699

41

18.18

3.47E-06

GO:0006310

DNA recombination

18

8

0.47

4.47E-06

GO:0006139

nucleobase-containing compound metabolic…

631

38

16.41

1.09E-05

GO:0006807

nitrogen compound metabolic process

725

41

18.85

1.19E-05

GO:0043170

macromolecule metabolic process

803

42

20.88

7.57E-05

GO:0006304

DNA modification

7

5

0.18

1.92E-04

GO:0004803

transposase activity

4

4

0.1

3.03E-04

GO:0006305

DNA alkylation

4

4

0.1

3.83E-04

GO:0006306

DNA methylation

4

4

0.1

3.83E-04

GO:0006313

transposition, DNA-mediated

4

4

0.1

3.83E-04

GO:0032196

transposition

4

4

0.1

3.83E-04

GO:0040029

regulation of gene expression, epigeneti…

4

4

0.1

3.83E-04

GO:0044237

cellular metabolic process

1096

48

28.5

1.09E-03

GO:0008152

metabolic process

2048

66

53.26

8.94E-03

GO:0043414

macromolecule methylation

7

4

0.18

1.28E-02

GO:0043412

macromolecule modification

63

9

1.64

2.28E-02

GO:0032259

methylation

16

5

0.42

3.28E-02

  1. Gene ontology (GO) classifications were used to determine whether certain functional categories are enriched in the pool of genes unique to IAF-45-CD. The category ‘All’ indicates annotations for the entire IAF-45-CD chromosome; ‘Unique’ indicates annotations for genes unique to IAF-45-CD; ‘Expected’ indicates the number of unique genes expected if sampled at random from the pool of all unique genes found in the five genomes. The Bonferroni corrected p-values indicate the probability that the observed unique gene frequency is due to chance.