Figure 3
From: A network biology workflow to study transcriptomics data of the diabetic liver
Nodes linking the seven significantly changed pathways. Each pathway is represented as a yellow rounded rectangle. Gene products and metabolites are visualized as ellipses and octagons, respectively. The transcription dataset is visualized on the gene nodes in the network using a color gradient from blue (down-regulated) over white (not changed) to red (up-regulated). Nodes with a significant p-value (< 0.05) have a light-green border color. Most nodes linking multiple pathways are either up-regulated (e.g. SREBF1, CDKN1A, AGPAT2) or not altered significantly (e.g. LPL, HMGCR).