Skip to main content

Table 1 NRPS/PKS gene clusters and cluster families

From: Phylum-wide comparative genomics unravel the diversity of secondary metabolism in Cyanobacteria

Types of clusters No. of clusters No. of clusters of Orphan No. of CF
Known product (CF) Unknown product (CF)
PKS 162 61 (6) 48 (13) 53 72
Hybrid 100 13 (7) 36 (14) 51 72
NRPS 190 17 (6) 52 (15) 121 142
Total 452 91 (19) 136 (42) 225 286
  1. Gene clusters encoding NRPS, PKS and hybrid NRPS/PKS were found in 89 out of 126 cyanobacterial genomes (Additional file 1: Table S1). Several gene clusters were shared among Cyanobacteria, forming cluster families (CFs). Some CFs correspond to biosynthetic pathways of known products, whereas others without associated products were recovered using BLASTP and a transitive link criterion to build families. The other half of the gene clusters were orphans, each forming a putative family by its own.