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Figure 1 | BMC Genomics

Figure 1

From: Deciphering the heterogeneity in DNA methylation patterns during stem cell differentiation and reprogramming

Figure 1

Diagram of extracting DNA methylation pattern and calculation of entropy. Step 1. Mapping paired-end DNA methylation reads to Human reference; Step 2. Extracting DNA methylation calls; Step 3. Obtaining 4 contiguous CpG dinucleotides involved segments; Step 4. Calculating DNA methylation entropy for each segment. Filled and open circles represent methylated and unmethylated CpG dinucleotides, respectively.

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BMC Genomics

ISSN: 1471-2164

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