Size distribution and sequencing coverage of predicted sites. Sites were predicted based on in silico digests of each enzyme against A) maize and B) rice reference genomes then plotted by log10 site count in 1 bp bins. Predicted site count is displayed in grey. Sites with aligned reads (MQ ≥20) are displayed in heatmap colors as a non-log scale fraction of predicted sites. The heatmap for covered sites represents the total fraction of aligned reads within a given bin.