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Table 2 All results Pā€‰<ā€‰0.01 (FDR adjusted) from the NetGestalt Pathway Analysis

From: Meta-analysis of human methylation data for evidence of sex-specific autosomal patterns

GO Biological Process

GO Accession

Number of genes

P value (FDR adjusted)

D

RNA splicing

GO:0008380

122

5.73E-04

0.21

DNA repair

GO:0006281

116

5.73E-04

0.17

Protein modification by small protein conjugation

GO:0032446

122

5.73E-04

0.17

Viral reproduction

GO:0016032

140

5.73E-04

0.15

mRNA processing

GO:0006397

163

1.13E-03

0.18

Interphase of mitotic cell cycle

GO:0051329

170

1.13E-03

0.16

Protein catabolic process

GO:0030163

196

1.86E-03

0.15

Interphase

GO:0051325

172

1.86E-03

0.15

RNA splicing, via transesterification reactions

GO:0000375

83

2.31E-03

0.22

Protein ubiquitination

GO:0016567

119

2.76E-03

0.15

Translation

GO:0006412

101

3.53E-03

0.16

rRNA metabolic process

GO:0016072

30

7.11E-03

0.33

Chromatin modification

GO:0016568

97

7.11E-03

0.15

M phase

GO:0000279

165

7.84E-03

0.13

Cellular protein catabolic process

GO:0044257

164

8.92E-03

0.14

rRNA processing

GO:0006364

28

9.76E-03

0.33

  1. GO: Gene Ontology. D: D-statistic; the maximum difference in cumulative fraction (of P value distribution). Only positive associations are shown (pathways enriched for genes containing CpG sites with lower P values compared to all CpG sites). The number of genes in each pathway that were represented by CpG sites in the meta-analysis is also shown.