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Table 3 Relationship of microsatellite heterozygosity with measures of variation across individuals

From: Sequence differences at orthologous microsatellites inflate estimates of human-chimpanzee differentiation

Variable   1 STR region 2 STR regions
  Tri Tetra Tetra
  n = 31 n = 79 n = 21
  Chimpanzee Human Chimpanzee Human Chimpanzee Human
Number of distinct alleles ρ 0.643 0.207 0.292 0.657 0.301 0.694
  P 9.51 ×  10 -5 0.263 0.009 4.97 ×  10 -11 0.184 6.89 ×  10 -4
Variance in the number of repeats ρ 0.594 0.240 0.336 0.730 0.596 0.851
  P 4.26 ×  10 -4 0.194 0.002 <10-16 0.004 <10-16
Range of the number of repeats ρ 0.433 0.152 0.166 0.602 0.440 0.784
  P 0.015 0.411 0.144 4.35 ×  10 -9 0.046 3.62 ×  10 -5
Mean PCR fragment length ρ 0.093 0.044 0.230 0.084 0.096 -0.134
  P 0.617 0.814 0.042 0.461 0.676 0.562
Mean number of repeats ρ 0.529 0.388 0.461 0.184 0.522 0.526
  P 0.002 0.032 1.88 ×  10 -5 0.105 0.015 0.016
Maximum number of repeats ρ 0.405 0.216 0.391 0.386 0.632 0.635
  P 0.024 0.243 3.68  × 10 -4 4.82  × 10 -4 0.002 0.002
Minimum number of repeats ρ 0.068 0.136 0.326 0.046 0.122 -0.156
  P 0.717 0.464 0.003 0.686 0.598 0.498
  1. Spearman’s rank correlation coefficients (ρ) are shown for comparisons of microsatellite He with measures of variation across individuals calculated separately among chimpanzees and humans. Microsatellites were grouped by their number of separate STR regions and repeat unit size. No comparisons were performed for microsatellites with one dinucleotide STR region, two trinucleotide STR regions, or three or four tetranucleotide STR regions because of small sample sizes (1, 1, 4, and 1, respectively). Correlations with P < 0.05 are shown in bold.