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Table 1 The human and bovine (UMD3.1) TRAV/TRDV repertoires

From: Genomic analysis offers insights into the evolution of the bovine TRA/TRD locus

Subgroup

Human

Bovine

Total

Functional

Pseudo.

Percentage functional

Total

Functional

Pseudo.

Incomplete

Percentage functional

(Number of genes)

(Number of genes)

AV1

2

2

 

100

1

1

  

100

AV2

1

1

 

100

7

5

2

 

71.4

AV3

1

1†

1†

100/0

7

7

  

100

AV4

1

1

 

100

3

2

1

 

66.7

AV5

1

1

 

100

2

2

  

100

AV6

1

1

 

100

4

 

3

1

0

AV7

1

1

 

100

     

AV8

7

5

2

71.4

14

6

8

 

42.9

AV9

2

2

 

100

11

1

9

1

9.1

AV10

1

1

 

100

6

3

3

 

50

AV11

1

 

1

0

6

 

6

 

0

AV12

3

3

 

100

6

5

 

1

83.3

AV13

2

2

 

100

11

8

2

1

72.8

AV14

1

1

 

100

9

4

4

1

44.4

AV15

1

 

1

0

     

AV16

1

1

 

100

2

2

  

100

AV17

1

1

 

100

3

1

2

 

33.3

AV18

1

1

 

100

8

3

5

 

37.5

AV19

1

1

 

100

7

5

2

 

71.4

AV20

1

1

 

100

5

5

  

100

AV21

1

1

 

100

4

3

1

 

75

AV22

1

1

 

100

29

14

14

1

48.3

AV23

1

1

 

100

24

4

20

 

16.7

AV24

1

1

 

100

10

1

8

1

10

AV25

1

1

 

100

22

11

10

1

50

AV26

2

2

 

100

39

22

13

4

56.4

AV27

1

1

 

100

1

1

  

100

AV28

1

 

1

0

4

3

1

 

75

AV29

1

1†

1†

100/0

3

2

1

 

66.7

AV30

1

1

 

100

     

AV31

1

 

1

0

     

AV32

1

 

1

0

     

AV33

1

 

1

0

6

2

4

 

33.3

AV34

1

1

 

100

3

 

3

 

0

AV35

1

1

 

100

1

1

  

100

AV36

1

1

 

100

1

1

  

100

AV37

1

 

1

0

2

 

2

 

0

AV38

2

2

 

100

6

5

 

1

83.3

AV39

1

1

 

100

2

1

1

 

50

AV40

1

1

 

100

     

AV41

1

1

 

100

1

1

  

100

AVX

    

29

23

5

1

79.3

AVY

    

7

7

  

100

DV1

1

1

 

100

60

48

8

4

80.0

DV2

1

1

 

100

1

1

  

100

DV3

1

1

 

100

1

1

  

100

DVb3

    

2

2

  

100

DVY

    

1

1

  

100

Total

57

46 (+2)

9 (+2)

80.7

371

215

138

18

58.0

  1. The numbers of total, functional and pseudogenes in each TRAV/TRDV subgroup in the germline human and bovine (UMD3.1) repertoires are shown. The percentage of genes in each subgroup that are functional has been calculated (for human genes that have alternative functional and non-functional alleles – denoted by †, two percentage values are shown). For the bovine TRAV/TRDV subgroups, the number of genes for which only incomplete genomic sequence was available is also shown. Details of the human TRAV/TRDV repertoire were taken from the IMGT database (http://www.imgt.org).
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BMC Genomics

ISSN: 1471-2164

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