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Table 4 Single nuclear variations (SNVs) involved in homogentisate pathway and the regulators of penicillin biosynthesis

From: Genome sequencing of high-penicillin producing industrial strain of Penicillium chrysogenum

Gene

Length

(bp)

Description

Discrepancies

(SNVs)

pahA

1,727

A phenylacetate 2-hydroxylase which catalyzes the first step of the homogentisate pathway for PAA catabolism

--

pahB

1,797

Strongly similar to pahA

--

pahC

1,785

Strongly similar to pahA

non-synonymous

(G482C)

pahD

2,423

Strongly similar to pahA

synonymous

(C1976T)

Pc laeA

1,340

A global regulator of secondary metabolism

--

Pc velA

1,745

An activator and repressor of secondary metabolism

non-synonymous (C1002T)