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Table 1 SVM and MDSM scores for validated set.

From: Cluster based prediction of PDZ-peptide interactions

PDZ domain

Peptide

SVM score

MDSM score

Pubmed Ref.

Cipp-(3/10)

IESDV

0.44

-0.7

9647694

Cipp-(3/10)

LESEV

0.30

-0.62

9647694

Cipp-(3/10)

QQSNV

0.29

-0.78

9647694

Cipp-(3/10)

KEYYV

0.51

-0.34

9647694

Dvl1-(1/1)

SETSV

-1.27

-0.74

12490194

Pdlim5-(1/1)

DITSL

-0.24

-0.15

10359609

Erbin-(1/1)

LDVPV

0.99

0.61

10878805

Magi-2-(5/6)

KESSL

1.76

0.19

10681527

MUPP1-(10/13)

IATLV

1.00

0.46

11000240

MUPP1-(10/13)

GKDYV

1.00

1.68

11689568

NHERF-1-(1/2)

FDTPL

1.06

0.01

10980202

LIN-7A-(1/1)

IESDV

0.33

0.29

10341223

Lin7c-(1/1)

IESDV

0.33

1.00

10341223

ZO-3-(1/3)

GKDYV

0.99

0.09

10601346

a1-syntrophin-(1/1)

VLSSV

-1.47

0.16

11571312

PSD95-(1/3)

LQTEV

0.38

1.41

11937501

PSD95-(1/3)

NETVV

-1.35

1.19

12067714

PSD95-(1/3)

GETAV

-1.32

1.23

12067714

PSD95-(1/3)

EESSV

-2.23

0.77

11134026

PSD95-(1/3)

RTTPV

1.00

0.61

12359873

  1. SVM and MDSM scores for experimentally validated interactions derived from PDZBase [35]. A peptide is predicted to bind to a PDZ domain if the score is more than 0 for SVM and more than 1 for MDSM. Bold numbers indicate true positive interactions.