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Figure 3 | BMC Genomics

Figure 3

From: Improving miRNA-mRNA interaction predictions

Figure 3

Description of the WSP and LRS methods. In the WSP method, box a), a new score for each interaction in each database is calculated by weighting their original scores with their associated accumulated precision. To this aim, for each of the databases, the interactions are sorted and their corresponding accumulated precisions are calculated. The obtained precision values are considered to be reliable in case they are larger than the randomly expected precision of the database. In the LRS method, box b), each interaction in each database is re-scored by assigning its probability of being experimentally-validated. To this aim, for each database, the probability of each interaction of being experimentally-validated is calculated. The probabilities in different databases are then combined considering their possible dependencies.

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