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Figure 2 | BMC Genomics

Figure 2

From: Mathematical model of the Tat-Rev regulation of HIV-1 replication in an activated cell predicts the existence of oscillatory dynamics in the synthesis of viral components

Figure 2

Schematic representation of Rev-mediated transport of intron-containing 4 kb and 9 kb RNAs and of the Rev protein recycling. (A) - hypothesis 1 for the Rev recycling at the nuclear pore complex; (B) - hypothesis 2 for the Rev recycling in the cytoplasm. RRE - Rev binding site on 4 kb and 9 kb RNAs; Crm1, RanGTP, RanGDP, Importin - are the major cellular factors mediating the RNA export and import of RNA.

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