Figure 6From: The structural network of Interleukin-10 and its implications in inflammation and cancerR198W substitution mutation on IL-10RB protein. IL-10 (2ilkA) is shown in green, blue protein is IL-10RB (3lqmA). R198, highlighted in yellow, is the substituted residue on the mutant IL-10RB. This mutation is very close to the interface between IL-10 and IL-10RB and it abolishes the interaction of IL-10RB with IL-10.Back to article page