Table 2 Comparison of the binding energy scores for wild type and mutant structures
From: The structural network of Interleukin-10 and its implications in inflammation and cancer
Target Structures | Binding Energy Score | |
|---|---|---|
IL-10 (1j7vL) (wt) | IL-10RA (1j7vR) (wt) | -25.54 |
IL-10 (2ilkA) (wt) | IL-10RB (3lqmA) (wt) | -15.98 |
IL-10 (2ilkA) (wt) | IL-10RB (3lqmA) (R198W) | -6.09 |
IL-10 (2ilkA) (wt) | IL-10RB (3lqmA) (E41*) | N/A |
IL-10 (2ilkA) (wt) | A2M (1bv8) (wt) | -39.2 |
IL-10 (2ilkA) (Q56*) | A2M (1bv8) (wt) | N/A |
A2M (4acqC) (wt) | APP (2llmA) (wt) | -39.12 |
A2M (4acqC) (R945Q) | APP (2llmA) (wt) | -9.12 |
hK13 (model) (wt) | A2M ( 1bv8A) (wt) | -65.22 |
hK13 (model) (R236L) | A2M ( 1bv8A) (wt) | +19.48 |