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Table 3 Classification performance measurements from two-group comparison (%).

From: In silico comparative characterization of pharmacogenomic missense variants

Classification Sensitivity Specificity Accuracy Precision F-measure AUC
Structure       
Disease/neutral 76.4 75.4 75.9 74.3 75.4 82.0
   PGx/disease 67.3 74.1 70.7 45.1 54.0 78.1
   PGx/neutral 58.2 66.3 62.2 33.7 42.7 64.2
Sequence       
Disease/neutral 73.5 68.4 70.9 75.7 74.6 79.3
   PGx/disease 68.3 72.4 70.3 32.3 43.9 77.4
   PGx/neutral 47.6 63.9 55.7 25.4 33.1 56.9