Table 3 Classification performance measurements from two-group comparison (%).
From: In silico comparative characterization of pharmacogenomic missense variants
Classification | Sensitivity | Specificity | Accuracy | Precision | F-measure | AUC |
|---|---|---|---|---|---|---|
Structure | Â | Â | Â | Â | Â | Â |
Disease/neutral | 76.4 | 75.4 | 75.9 | 74.3 | 75.4 | 82.0 |
   PGx/disease | 67.3 | 74.1 | 70.7 | 45.1 | 54.0 | 78.1 |
   PGx/neutral | 58.2 | 66.3 | 62.2 | 33.7 | 42.7 | 64.2 |
Sequence | Â | Â | Â | Â | Â | Â |
Disease/neutral | 73.5 | 68.4 | 70.9 | 75.7 | 74.6 | 79.3 |
   PGx/disease | 68.3 | 72.4 | 70.3 | 32.3 | 43.9 | 77.4 |
   PGx/neutral | 47.6 | 63.9 | 55.7 | 25.4 | 33.1 | 56.9 |