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Figure 2 | BMC Genomics

Figure 2

From: NeEMO: a method using residue interaction networks to improve prediction of protein stability upon mutation

Figure 2

Representation of the NeEMO pipeline. The 3D structure of a protein is transformed into a RIN. Node centralities are then computed and combined with other RIN features, such as secondary structure, relative solvent accessibility and sequence conservation. All numerical descriptors are then fed into a neural network that predicts the ΔΔG for the chosen mutation.

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BMC Genomics

ISSN: 1471-2164

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