Figure 2From: NeEMO: a method using residue interaction networks to improve prediction of protein stability upon mutationRepresentation of the NeEMO pipeline. The 3D structure of a protein is transformed into a RIN. Node centralities are then computed and combined with other RIN features, such as secondary structure, relative solvent accessibility and sequence conservation. All numerical descriptors are then fed into a neural network that predicts the ΔΔG for the chosen mutation.Back to article page