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Figure 1 | BMC Genomics

Figure 1

From: Prediction of HIV drug resistance from genotype with encoded three-dimensional protein structure

Figure 1

Crystal structures of HIV-1 PR and RT. The structure of HIV-1 PR dimer in complex with the inhibitor (PI) saquinavir is shown from50. The two subunits of HIV-1 PR are shown in green and cyan. The PI is colored red. The structure of HIV-1 RT dimer is shown in complex with DNA and bound NNRTI nevirapine (NVP) and NRTI zidovudine (AZT) from 51-52. The p66 subunit is shown in green and the p51 subunit is shown in purple. NRTI is shown in blue, and NNRTI is red. Double stranded DNA is indicated in orange.

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