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Table 1 The major up- and down-regulated genes after acriflavine exposure

From: RNA-sequencing analysis of Trichophyton rubrumtranscriptome in response to sublethal doses of acriflavine

ID

3 hours

12 hours

24 hours

Gene Product Name

TERG_00209

5.76

6.03

11.66

Hypothetical protein (tenascin C gene family)

TERG_00698

6.75

9.42

10.63

L-ornithine 5-monooxygenase

TERG_01685

8.26

9.98

9.21

glutathione transferase

TERG_00500

8.43

9.57

10.31

Hypothetical protein

TERG_02583

5.95

6.40

9.56

phosphate permease

TERG_04160

9.50

8.32

0

Hypothetical protein

TERG_03272

9.40

9.26

9.18

pre-mRNA branch site protein p14

TERG_07875

9.21

9.25

9.24

integral membrane protein

TERG_02897

9.08

9.30

9.24

methylene-fatty-acyl-phospholipid synthase

TERG_05361

7.20

9.03

8.84

cript family protein

TERG_05520

8.62

8.79

8.53

Hypothetical protein

TERG_02132

5.34

8.22

8.70

Hypothetical protein (Generic methytransferase gene family)

TERG_03274

8.44

7.16

7.88

ammonium transporter MeaA

TERG_05514

8.25

8.22

8.20

oligosaccharyltransferase subunit ribophorin II

TERG_01219

8.15

7.41

8.40

malate/L-lactate dehydrogenase

TERG_05137

8.11

5.30

0

microsomal dipeptidase

TERG_08522

7.86

6.88

7.61

pyruvate dehydrogenase E1 B-subunit

TERG_05478

6.96

6.06

6.28

chromatin remodeling complex subunit Arp5

TERG_01497

5.50

5.38

6.39

protein kinase subdomain-containing protein

TERG_05744

2.26

2.76

4.29

GTP-binding protein EsdC

TERG_07143

4.09

2.94

3.15

potassium/sodium efflux P-type ATPase

TERG_00697

1.24

2.79

3.51

non-ribosomal peptide synthetase

TERG_08353

0.66

0.98

2.97

cytochrome P450

TERG_05270

1.08

0.94

2.84

C2H2 finger domain-containing protein

TERG_03172

0.49

0.47

2.79

sodium/phosphate symporter

TERG_08201

1.20

1.55

2.63

serine protease

TERG_05854

-3.63

-3.98

-11.20

beta-lactamase

TERG_01454

-3.56

-2.81

-9.47

microsomal dipeptidase

TERG_08129

-3.48

-3.71

-4.64

amino acid permease

TERG_01401

-3.78

-2.15

-4.06

high affinity copper transporter

TERG_07734

-2.47

-4.04

-3.93

O-methyltransferase

TERG_01609

-0.26

-2.80

-3.66

Na/K ATPase alpha 1 subunit

TERG_02400

-1.93

-3.01

-3.62

amino acid permease

TERG_03352

-2.23

-2.74

-3.48

tyrosine decarboxylase

TERG_04146

-2.40

-2.77

-3.47

FAD binding domain-containing protein

TERG_01346

-1.36

-2.83

-3.40

lipase/serine esterase

TERG_06701

-2.68

-3.38

-3.19

gamma-glutamyltranspeptidase

TERG_04238

-1.28

-1.47

-3.38

cation-transporting ATPase

TERG_00066

-0.67

-2.58

-3.32

4-hydroxyphenylpyruvate dioxygenase

TERG_07214

-1.47

-1.78

-3.29

DlpA domain-containing protein

TERG_00227

-1.72

-3.05

-3.25

glutathione S-transferase

TERG_05332

-1.23

-1.61

-3.12

mitochondrial carrier protein

TERG_00546

-1.08

-0.78

-3.04

Glutaredoxin

TERG_06938

-0.59

-1.95

-3.01

zinc metallopeptidase

TERG_05409

-1.84

-2.94

-2.98

FAD dependent oxidoreductase