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Table 1 Common drugs in the Cancer Genome Project (CGP) and Cancer Cell Line Encyclopedia (CCLE) datasets

From: Computational identification of multi-omic correlates of anticancer therapeutic response

Compound Target(s) Class Organization
17-AAG* HSP90 Targeted other Bristol-Myers Squibb
AZD0530 Src, Abl, EGFR Kinase Inhibitor AstraZeneca
AZD6244* MEK Kinase Inhibitor AstraZeneca
Crizotinib* c-MET, ALK Kinase Inhibitor Pfizer
Erlotinib* EGFR Kinase Inhibitor Genentech
Lapatinib* EGFR, HER2 Kinase Inhibitor GlaxoSmithKline
Nilotinib* Abl/Bcr-Abl Kinase Inhibitor Novartis
Nutlin-3* MDM2 Targeted other Roche
NVP-TAE684* ALK Kinase Inhibitor Novartis
Paclitaxel* Beta-Tubulin Cytotoxic Bristol-Myers Squibb
PD-0325901 MEK Kinase Inhibitor Pfizer
PD-0332991 CDK4/6 Kinase Inhibitor Pfizer
PHA-665752 c-MET Kinase Inhibitor Pfizer
PLX4720 RAF Kinase Inhibitor Plexxikon
Sorafenib* FLT3, c-KIT, PDGFR, RET, Raf kinases, VEGFR, KDR, FLT4 Kinase Inhibitor Bayer
  1. * Indicates compound found in CGP, CCLE and NCI60 datasets