Gene and protein codes | Official full name | Number of cavities with Drug Scorea > 0.80 | Number of cavities with Drug Scorea > 0.60 and < 0.80 | Mol. Wt (KDa)b | Functionsc | Cellular componentd | Pathwayse | Virulencef |
---|---|---|---|---|---|---|---|---|
Cp1002_0385 Adk | Adenylate kinase | 1 | 0 | 24.120 | MF: Kinase, Transferase, ATP binding BP: Nucleotide biosynthesis EC 2.7.4.3 | Cytoplasm | Purine metabolism; AMP biosynthesis via salvage pathway | Yes |
Cp1002_0692 GapA | Glyceraldehyde-3-phosphate dehydrogenase A | 2 | 1 | 51.918 | MF: Oxidoreductase, NAD binding, NADP binding, BP: glucose metabolic process EC 1.2.1.13 | Cytoplasm | Glycolysis/Gluconeogenesis | Yes |
Cp1002_0728 GlyA | Serine hydroxymethyltransferase | 2 | 1 | 46.187 | MF: Methyltransferase, Transferase BP: Amino-acid biosynthesis One-carbon metabolism EC 2.1.2.1 | Cytoplasm | Amino-acid biosynthesis; glycine biosynthesis; One-carbon metabolism; tetrahydrofolate interconversion. | Yes |
Cp1002_0738 FumC | Fumaratehydratase class II | 2 | 0 | 49.767 | MF: Lyase BP: Tricarboxylic acid cycle EC 4.2.1.2 | Cytoplasm | Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate | Yes |
Cp1002_1005 Gnd | 6-phosphogluconate dehydrogenase | 3 | 5 | 53.669 | MF: Oxidoreductase BP: Pentose shunt EC 1.1.1.44 | Cytoplasm | Carbohydrate degradation; pentose phosphate pathway; | No |
Cp1002_1042 AspA | Aspartate ammonia-lyase | 2 | 4 | 52.277 | MF: Lyase EC 4.3.1.1 | Cytoplasm | Alanine, aspartate and glutamate metabolism, Nitrogen metabolism | Yes |