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Table 1 Proportions of TAL1 differential binding in the three categories overlapping with relevant biological features.

From: dCaP: detecting differential binding events in multiple conditions and proteins

  A. binary-only B. cap-only C. common
induced genes 1 18.77% *** 32.83% 26.20%
repressed genes 1 9.85% 9.94% 6.89%
all differential expressed genes 1 28.62% *** 42.76% 33.09%
non-differential expressed genes 1 52.08% 49.46% 50.75%
GATA1 binding peaks 2 36.03% *** 95.68% 63.17%
GATA motifs 3 66.27% *** 86.61% 59.51%
CpG islands 4 2.39% 3.67% 2.19%
SNPs 4 84.52% ** 89.42% 82.23%
  1. Significance of difference in proportions between group A and B is denoted by * for each biological feature examined. ** denotes p-values between 5e-2 and 5e-3. *** denotes p-values < 5e-3. The p-values were obtained from the Fisher's Exact Test. The differential expressed genes in G1E and G1E-ER4 were obtained from the transcriptome data in G1E and G1E-ER4 cells1 [15]. GATA1 binding peaks were obtained from [15]. GATA motifs3 were identified by MEME relevant tools [49]. Annotation data such as CpG islands4 and SNPs4 (dbSNP 128) were from database of UCSC genome browser [50].